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O'Hare International Airport to São Tomé International Airport flight
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Cheap Flight Deals from O'Hare International Airport to São Tomé International Airport

Search for flights from Chicago to Sao Tome Island and check out affordable one-way and round-trip options.

  • One way
  • Round-trip
sortSort: Price (Lowest)
  • Sort: Price (Lowest)
  • Sort: Departure (Earliest)
      • ORD18:00
        30h 25m
        1 stop
        TMS05:25
        Chicago - Sao Tome Island|Mon, Jul 15|TAP Air Portugal
        US$1,108US$1,761
        37% OFF
        37% OFF
        US$1,761US$1,108
      • ORD18:00
        18h 40m
        1 stop
        TMS17:40
        Chicago - Sao Tome Island|Sat, Jul 13|TAP Air Portugal
        US$1,140US$1,761
        35% OFF
        35% OFF
        US$1,761US$1,140
      • ORD18:00
        18h 25m
        1 stop
        TMS17:25
        Chicago - Sao Tome Island|Fri, Jul 12|TAP Air Portugal
        US$1,270US$1,761
        28% OFF
        28% OFF
        US$1,761US$1,270
      • ORD18:07
        30h 18m
        2 stops
        TMS05:25
        Chicago - Sao Tome Island|Mon, Jul 15|United Airlines
        US$1,304
        US$1,304
      • ORD20:31
        64h 9m
        2 stops
        TMS17:40
        Chicago - Sao Tome Island|Tue, Jul 9|American Airlines
        US$1,333
        US$1,333
      • ORD08:20
        28h 20m
        2 stops
        TMS17:40
        Chicago - Sao Tome Island|Sat, May 18|American Airlines
        US$1,339
        US$1,339
      • ORD08:14
        28h 26m
        2 stops
        TMS17:40
        Chicago - Sao Tome Island|Sat, Jul 13|American Airlines
        US$1,353
        US$1,353
      • ORD16:35
        31h 50m
        2 stops
        TMS05:25
        Chicago - Sao Tome Island|Mon, Jul 15|Iberia
        US$1,363
        US$1,363
      • ORD21:25
        27h
        2 stops
        TMS05:25
        Chicago - Sao Tome Island|Mon, Jul 15|Lufthansa
        US$1,374
        US$1,374
      • ORD08:14
        28h 11m
        2 stops
        TMS17:25
        Chicago - Sao Tome Island|Fri, Jul 12|American Airlines
        US$1,388
        US$1,388
      • ORD13:00
        3h 5m
        Direct
        TMS14:00
        Chicago - Sao Tome Island|Mon, May 20|TAP Air Portugal
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Selected Airlines from O'Hare International Airport to São Tomé International Airport

See which airlines fly from Chicago to Sao Tome Island. Find the airline that best meets your travel needs by comparing prices and treat yourself to an enjoyable journey.

TAP Air Portugal
From US$1,108
United Airlines
From US$1,304
American Airlines
From US$1,333
Iberia
From US$1,363
Lufthansa
From US$1,374
Ethiopian Airlines
From US$1,449
Delta Air Lines
From US$1,714
Virgin Atlantic
From US$1,748
Aer Lingus
From US$1,809
Jetblue Airways
From US$1,851
ANA airlines
Find more flights and airlines
Flight Schedule from O'Hare International Airport to São Tomé International Airport

Check the schedule for flights from Chicago to Sao Tome Island and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. ET575

    Ethiopian Airlines

    10:15

    ORD

    13.8h

    08:00

    ADD

    SMTW-FS
    Search

  2. ET508

    Ethiopian Airlines

    08:45

    ADD

    5.5h

    11:15

    LFW

    -M-WT--

  3. ET1020

    Ethiopian Airlines

    13:55

    LFW

    1.8h

    15:40

    TMS

    -M-W-F-

  4. ET575

    Ethiopian Airlines

    10:15

    ORD

    13.8h

    08:00

    ADD

    SMTW-FS
    Search

  5. ET516

    Ethiopian Airlines

    08:35

    ADD

    5.5h

    11:05

    LFW

    S-T--F-

  6. ET1020

    Ethiopian Airlines

    13:55

    LFW

    1.8h

    15:40

    TMS

    -M-W-F-

  7. UA1857

    United Airlines

    10:45

    ORD

    3.2h

    14:58

    MIA

    SMTWTFS
    Search

  8. TP224

    TAP Air Portugal

    16:30

    MIA

    8.3h

    05:50

    LIS

    SMTWTFS

  9. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.8h

    17:40

    TMS

    --T-T-S

  10. TP8481

    TAP Air Portugal

    11:07

    ORD

    2.4h

    14:30

    EWR

    SMTWTFS
    Search

  11. TP202

    TAP Air Portugal

    17:40

    EWR

    6.9h

    05:35

    LIS

    SMTWTFS

  12. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.8h

    17:40

    TMS

    --T-T-S

  13. UA1258

    United Airlines

    13:15

    ORD

    2.5h

    16:47

    EWR

    SMTWTFS
    Search

  14. LH7966

    Lufthansa

    20:40

    EWR

    6.7h

    08:20

    LIS

    SMTWTFS

  15. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.8h

    17:40

    TMS

    --T-T-S

  16. VS4674

    Virgin Atlantic

    14:00

    ORD

    2.7h

    17:41

    JFK

    SMTWTFS
    Search

  17. VS3895

    Virgin Atlantic

    19:50

    JFK

    7.2h

    08:00

    LIS

    SMTWTFS

  18. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.8h

    17:40

    TMS

    --T-T-S

  19. AA1705

    American Airlines

    15:22

    ORD

    2.0h

    18:25

    LGA

    SMTWTFS
    Search

  20. TP210

    TAP Air Portugal

    22:05

    JFK

    6.9h

    10:00

    LIS

    SMTWTFS

  21. TP1531

    TAP Air Portugal

    11:40

    LIS

    6.8h

    17:25

    TMS

    -----F-

  22. UA2039

    United Airlines

    18:00

    ORD

    2.4h

    21:21

    LGA

    SMTWTFS
    Search

  23. UA064

    United Airlines

    20:40

    EWR

    6.7h

    08:20

    LIS

    SMTWTFS

  24. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.8h

    17:40

    TMS

    --T-T-S

  25. UA2039

    United Airlines

    18:00

    ORD

    2.4h

    21:21

    LGA

    SMTWTFS
    Search

  26. ET509

    Ethiopian Airlines

    21:45

    EWR

    10.1h

    11:50

    LFW

    -M-WT--

  27. KP060

    Asky Airlines

    13:55

    LFW

    1.8h

    15:40

    TMS

    -M-W-F-

  28. TP244

    TAP Air Portugal

    18:00

    ORD

    7.9h

    07:55

    LIS

    S-T-T-S
    Search

  29. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.8h

    17:40

    TMS

    --T-T-S
Find more flights and airlines

O'Hare International Airport to São Tomé International Airport Flights Info

Flight distance10,372.48km
Cheapest one-way ticket priceUS$1,108
Cheapest return ticket priceUS$2,050

FAQs for O'Hare International Airport to São Tomé International Airport Flights

  • What is the transportation method from the main airport to downtown in Sao Tome Island?

    • The distance from São Tomé International Airport to downtown is about 5km, by taxi about 20 minutes.

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