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Flights from Medellin to Santiago
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Find Medellin to Santiago flights starting at CAD 179.

We've found these cheap flights for you. You can book one-way or return flight tickets.

  • One way
  • Round-trip
      • Cheapest nonstop
        MDE13:43
        6h 8m
        Nonstop
        SCL21:51
        Fri, Dec 27|Medellin - Santiago|JetSMART
        CAD 179CAD 224
        20% OFF
        20% OFF
        CAD 224CAD 179

        Choose JetSMART flights from Medellin to Santiago. The one-way direct flight with JetSMART departs from Jose Marie Cordova Airport on Fri, Dec 27, arriving at Arturo Merino Benitez Airport. One-way Prices start from CAD 179 including taxes and charges.

      • MDE13:13
        6h 8m
        Nonstop
        SCL21:21
        Wed, Jan 1|Medellin - Santiago|JetSMART
        CAD 184CAD 224
        18% OFF
        18% OFF
        CAD 224CAD 184

        Choose JetSMART flights from Medellin to Santiago. The one-way direct flight with JetSMART departs from Jose Marie Cordova Airport on Wed, Jan 1, arriving at Arturo Merino Benitez Airport. One-way Prices start from CAD 184 including taxes and charges.

      • MDE13:13
        6h 8m
        Nonstop
        SCL21:21
        Fri, Jan 17|Medellin - Santiago|JetSMART
        CAD 185CAD 224
        18% OFF
        18% OFF
        CAD 224CAD 185

        Choose JetSMART flights from Medellin to Santiago. The one-way direct flight with JetSMART departs from Jose Marie Cordova Airport on Fri, Jan 17, arriving at Arturo Merino Benitez Airport. One-way Prices start from CAD 185 including taxes and charges.

      • MDE13:43
        6h 8m
        Nonstop
        SCL21:51
        Wed, Dec 25|Medellin - Santiago|JetSMART
        CAD 191
        CAD 191

        Choose JetSMART flights from Medellin to Santiago. The one-way direct flight with JetSMART departs from Jose Marie Cordova Airport on Wed, Dec 25, arriving at Arturo Merino Benitez Airport. One-way Prices start from CAD 191 including taxes and charges.

      • MDE13:13
        6h 8m
        Nonstop
        SCL21:21
        Wed, Jan 15|Medellin - Santiago|JetSMART
        CAD 201
        CAD 201

        Choose JetSMART flights from Medellin to Santiago. The one-way direct flight with JetSMART departs from Jose Marie Cordova Airport on Wed, Jan 15, arriving at Arturo Merino Benitez Airport. One-way Prices start from CAD 201 including taxes and charges.

      • MDE13:13
        6h 8m
        Nonstop
        SCL21:21
        Sat, Jan 11|Medellin - Santiago|JetSMART
        CAD 201
        CAD 201

        Choose JetSMART flights from Medellin to Santiago. The one-way direct flight with JetSMART departs from Jose Marie Cordova Airport on Sat, Jan 11, arriving at Arturo Merino Benitez Airport. One-way Prices start from CAD 201 including taxes and charges.

      • MDE13:13
        6h 8m
        Nonstop
        SCL21:21
        Mon, Jan 13|Medellin - Santiago|JetSMART
        CAD 201
        CAD 201

        Choose JetSMART flights from Medellin to Santiago. The one-way direct flight with JetSMART departs from Jose Marie Cordova Airport on Mon, Jan 13, arriving at Arturo Merino Benitez Airport. One-way Prices start from CAD 201 including taxes and charges.

      • MDE13:13
        6h 8m
        Nonstop
        SCL21:21
        Wed, Jan 8|Medellin - Santiago|JetSMART
        CAD 201
        CAD 201

        Choose JetSMART flights from Medellin to Santiago. The one-way direct flight with JetSMART departs from Jose Marie Cordova Airport on Wed, Jan 8, arriving at Arturo Merino Benitez Airport. One-way Prices start from CAD 201 including taxes and charges.

      • MDE13:13
        6h 8m
        Nonstop
        SCL21:21
        Mon, Jan 6|Medellin - Santiago|JetSMART
        CAD 201
        CAD 201

        Choose JetSMART flights from Medellin to Santiago. The one-way direct flight with JetSMART departs from Jose Marie Cordova Airport on Mon, Jan 6, arriving at Arturo Merino Benitez Airport. One-way Prices start from CAD 201 including taxes and charges.

      • MDE13:43
        6h 8m
        Nonstop
        SCL21:51
        Mon, Dec 30|Medellin - Santiago|JetSMART
        CAD 202
        CAD 202

        Choose JetSMART flights from Medellin to Santiago. The one-way direct flight with JetSMART departs from Jose Marie Cordova Airport on Mon, Dec 30, arriving at Arturo Merino Benitez Airport. One-way Prices start from CAD 202 including taxes and charges.

      • MDE01:00 pm
        3h 5m
        Nonstop
        SCL02:00 pm
        Mon, Dec 30|Medellin - Santiago|JetSMART
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Medellin to Santiago?

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find Cheapest Airlines Flying from Medellin to Santiago

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

JetSMART Airlines
From CAD 179
LATAM Airlines
From CAD 220
Copa Airlines
From CAD 243
avianca
From CAD 246
EasyFly
From CAD 254
APG Airline
From CAD 351
United Airlines
From CAD 2,296

Find more flights and airlines

Alternative Routes for Medellin to Santiago Flights

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Medellin to Santiago.

  • Cheapest
    JetSMART
    MDE
    13:43
    6h 8m
    Nonstop
    SCL
    21:51
    Jose Marie Cordova Airport - Arturo Merino Benitez Airport
    Fri, Dec 27JetSMART
    CAD 179
  • EasyFly
    EOH
    05:55
    11h 2m
    1 transfer
    SCL
    18:57
    Olaya Herrera Airport - Arturo Merino Benitez Airport
    Fri, Jan 31EasyFly
    CAD 254
  • EasyFly
    EOH
    05:55
    11h 2m
    1 transfer
    SCL
    18:57
    Olaya Herrera Airport - Arturo Merino Benitez Airport
    Fri, Jan 31EasyFly
    CAD 254
    Find More Flights

FAQ

  • When are flight tickets from Medellin (MDE) to Santiago (SCL) the cheapest?

    Airlines adjust prices for flights from Medellin to Santiago based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much are flights from Medellin (MDE) to Santiago (SCL) cost?

    According to Trip.com's data, the lowest price is around CAD 457.

  • How long is the flight from Medellin (MDE) to Santiago (SCL)?

    It takes about 5 hours 59 minutes to fly from Medellin (MDE) to Santiago (SCL).

  • What is the transportation method from the main airport to downtown in Santiago?

    • The distance from Arturo Merino Benitez Airport to downtown is about 12km, by taxi about 30 minutes.

  • What are the most popular airlines that fly from Medellin (MDE) to Santiago (SCL)?

    Airlines with flights from Medellin (MDE) to Santiago (SCL): JetSMART Airlines and avianca.

  • What's the most popular airline for direct flights from Medellin (MDE) to Santiago (SCL)?

    JetSMART Airlines operates 1 direct flights from Medellin (MDE) to Santiago (SCL).

  • How many airports in Santiago (SCL)?

    There are 1 airport(s) in Santiago (SCL): Arturo Merino Benitez Airport.

How to find a cheap flight from Medellin to Santiago

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Medellin to Santiago. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Information for Medellin to Santiago Flights

Cheapest direct flight priceCAD 179
Cheapest return ticket priceCAD 337
Off-season travel monthDecember
Peak season for travelSeptember
Flight distance4,435.22km
Average flight time5 hours 59 minutes
Popular airlineavianca

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