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Flights from Myrtle Beach to Lafayette

No flight routes were found from Myrtle Beach to Lafayette. You can view deals below featuring nearby routes from Myrtle Beach to Indianapolis.

      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Tue, Dec 30 | Spirit Airlines
        IND 16:51
        7h 8m
        1 stop
        MYR 23:59
        Indianapolis - Myrtle Beach | Mon, Jan 5 | Spirit Airlines
        BRL 992 BRL 2,032
        51% OFF
        51% OFF
        BRL 2,032 BRL 992
      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Fri, Dec 26 | Spirit Airlines
        IND 12:38
        5h 30m
        1 stop
        MYR 18:08
        Indianapolis - Myrtle Beach | Wed, Dec 31 | Spirit Airlines
        BRL 1,217 BRL 2,032
        40% OFF
        40% OFF
        BRL 2,032 BRL 1,217
      • MYR 14:15
        7h 20m
        1 stop
        IND 21:35
        Myrtle Beach - Indianapolis | Sat, Dec 13 | Spirit Airlines
        IND 12:03
        5h 45m
        1 stop
        MYR 17:48
        Indianapolis - Myrtle Beach | Wed, Dec 17 | Spirit Airlines
        BRL 1,322 BRL 2,032
        35% OFF
        35% OFF
        BRL 2,032 BRL 1,322
      • MYR 05:11
        4h 11m
        1 stop
        IND 09:22
        Myrtle Beach - Indianapolis | Fri, Dec 26 | American Airlines
        IND 16:51
        7h 8m
        1 stop
        MYR 23:59
        Indianapolis - Myrtle Beach | Wed, Dec 31 | Spirit Airlines
        BRL 1,536
        24% OFF
        BRL 2,032 BRL 1,536
      • MYR 14:15
        7h 20m
        1 stop
        IND 21:35
        Myrtle Beach - Indianapolis | Fri, Dec 12 | Spirit Airlines
        IND 05:15
        5h 27m
        1 stop
        MYR 10:42
        Indianapolis - Myrtle Beach | Sun, Dec 14 | American Airlines
        BRL 1,589
        22% OFF
        BRL 2,032 BRL 1,589
      • MYR 06:23
        3h 58m
        1 stop
        IND 10:21
        Myrtle Beach - Indianapolis | Thu, Feb 5 | American Airlines
        IND 06:00
        5h 35m
        1 stop
        MYR 11:35
        Indianapolis - Myrtle Beach | Sun, Feb 8 | American Airlines
        BRL 1,665
        18% OFF
        BRL 2,032 BRL 1,665
      • MYR 19:13
        12h
        1 stop
        IND 07:13
        Myrtle Beach - Indianapolis | Tue, Dec 23 | Spirit Airlines
        IND 12:38
        5h 30m
        1 stop
        MYR 18:08
        Indianapolis - Myrtle Beach | Tue, Dec 30 | Spirit Airlines
        BRL 1,678
        17% OFF
        BRL 2,032 BRL 1,678
      • MYR 18:49
        5h 17m
        1 stop
        IND 00:06
        Myrtle Beach - Indianapolis | Mon, Jan 12 | Delta Air Lines
        IND 06:00
        3h 48m
        1 stop
        MYR 09:48
        Indianapolis - Myrtle Beach | Thu, Jan 15 | Delta Air Lines
        BRL 1,740
        14% OFF
        BRL 2,032 BRL 1,740
      • MYR 06:00
        3h 48m
        1 stop
        IND 09:48
        Myrtle Beach - Indianapolis | Fri, Dec 26 | Delta Air Lines
        IND 06:00
        4h 24m
        1 stop
        MYR 10:24
        Indianapolis - Myrtle Beach | Wed, Dec 31 | Delta Air Lines
        BRL 1,770
        13% OFF
        BRL 2,032 BRL 1,770
      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Fri, Dec 19 | Spirit Airlines
        IND 12:38
        5h 30m
        1 stop
        MYR 18:08
        Indianapolis - Myrtle Beach | Tue, Dec 23 | Spirit Airlines
        BRL 1,829
        10% OFF
        BRL 2,032 BRL 1,829
      • MYR 13:00
        17h 25m
        1 stop
        IND Invalid Date
        Myrtle Beach - Indianapolis | Sat, Dec 13 | Normal Airline
        IND 15:00
        6h
        Direct
        MYR 16:00
        Indianapolis - Myrtle Beach | Mon, Dec 15 | Normal Airline
        Find More Flights
        Find More Flights
      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Thu, Dec 25 | Spirit Airlines
        BRL 495 BRL 946
        48% OFF
        48% OFF
        BRL 946 BRL 495
      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Wed, Dec 24 | Spirit Airlines
        BRL 601 BRL 946
        36% OFF
        36% OFF
        BRL 946 BRL 601
      • MYR 18:59
        12h 44m
        1 stop
        IND 07:43
        Myrtle Beach - Indianapolis | Fri, Dec 12 | Spirit Airlines
        BRL 629 BRL 946
        34% OFF
        34% OFF
        BRL 946 BRL 629
      • MYR 06:00
        3h 48m
        1 stop
        IND 09:48
        Myrtle Beach - Indianapolis | Thu, Dec 25 | Delta Air Lines
        BRL 680
        28% OFF
        BRL 946 BRL 680
      • MYR 19:13
        12h
        1 stop
        IND 07:13
        Myrtle Beach - Indianapolis | Sat, Dec 20 | Spirit Airlines
        BRL 727
        23% OFF
        BRL 946 BRL 727
      • MYR 19:13
        12h
        1 stop
        IND 07:13
        Myrtle Beach - Indianapolis | Sun, Dec 21 | Spirit Airlines
        BRL 758
        20% OFF
        BRL 946 BRL 758
      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Fri, Dec 26 | Spirit Airlines
        BRL 825
        13% OFF
        BRL 946 BRL 825
      • MYR 06:00
        9h 56m
        1 stop
        IND 15:56
        Myrtle Beach - Indianapolis | Thu, Dec 18 | Spirit Airlines
        BRL 826
        13% OFF
        BRL 946 BRL 826
      • MYR 12:25
        7h 33m
        1 stop
        IND 19:58
        Myrtle Beach - Indianapolis | Mon, Jan 5 | Delta Air Lines
        BRL 840
        11% OFF
        BRL 946 BRL 840
      • MYR 12:30
        19h 13m
        1 stop
        IND 07:43
        Myrtle Beach - Indianapolis | Fri, Dec 12 | Delta Air Lines
        BRL 851
        10% OFF
        BRL 946 BRL 851
      • MYR 13:00
        17h 25m
        1 stop
        IND Invalid Date
        Myrtle Beach - Indianapolis | Sat, Dec 13 | Normal Airline
        Find More Flights
        Find More Flights

Displayed flight fares from Myrtle Beach to Lafayette are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight Information for Myrtle Beach to Lafayette Flights

View flight information for routes from Myrtle Beach to Indianapolis, including distance, duration, and the best value month, to plan your journey from Myrtle Beach to Lafayette.

Cheapest one-way flight priceBRL 495
Cheapest return ticket priceBRL 992
Off-season travel monthAugust
Peak season for travelJuly
Flight distance934.41km
Average flight time3 hours 55 minutes

When is the cheapest time to fly from Myrtle Beach to Lafayette?

Review price trends for flights from Myrtle Beach to Indianapolis—covering distance, duration, and the best value month—to assist in planning your trip from Myrtle Beach to Lafayette.

Cheapest flights
From price
Search
  • 714
  • 1421
  • 2128

  • Jan

    284
  • 411
  • 1118
  • 1825

  • Feb

    251
  • 18
  • 815
  • 1522

  • Mar

    221
Displayed fare trends are based on Trip.com's aggregated average of the lowest flight prices from Myrtle Beach to Lafayette, calculated over the upcoming 10 weeks.

Flight FAQs

Frequently asked questions about flights from Myrtle Beach to Lafayette when no local airport is available. Flights depart from and arrive at Myrtle Beach and Indianapolis.

  • Which airlines offer the cheapest flights from Myrtle Beach (MYR) to Indianapolis (IND)?

    Based on Trip.com data, Spirit Airlines offers one-way fares as low as BRL 495 on Cheapest nonstop routes (e.g. MYR to IND on Thu, Dec 25), while Spirit Airlines offers Cheapest nonstop round-trips from BRL 992 departing on Tue, Dec 30 and returning on Mon, Jan 5.
  • It takes about 3 hours 55 minutes to fly from Myrtle Beach (MYR) to Indianapolis (IND).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Myrtle Beach to Indianapolis is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Myrtle Beach to Indianapolis, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Thu, Dec 25, with one-way flights priced at just BRL 495.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Spirit Airlines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Indianapolis travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Myrtle Beach to Indianapolis is August, when demand for travel is lower.
  • After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Myrtle Beach to Indianapolis on December 30, 2025 with Spirit Airlines, with prices starting at BRL 991.
  • The time difference between Indianapolis and Myrtle Beach is 0h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.