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Flights from Santiago to Mexico City

Find Cheapest Airlines Flying from Santiago to Mexico City

Choose from 1 airlines flying from Santiago to Mexico City, including Aeromexico, and . Aeromexico currently offers the cheapest ticket on this route.
Aeromexico logo Aeromexico
Airlines are determined based on actual purchased flight tickets from Santiago to Mexico City according to previous 12 months data from Trip.com.

Find the cheapest direct flight options from Santiago to Mexico City over the next three months. Book one-way tickets from CAD 352 and round-trip tickets from CAD 679.

      • Cheapest nonstop
        SCL 23:25
        8h 40m
        Direct
        MEX 05:05
        Santiago - Mexico City | Wed, Dec 24 | Aeromexico
        MEX 10:10
        8h 5m
        Direct
        SCL 21:15
        Mexico City - Santiago | Fri, Dec 26 | Aeromexico
        CAD 679 CAD 745
        9% OFF
        9% OFF
        CAD 745 CAD 679
      • SCL 09:10
        8h 40m
        Direct
        MEX 14:50
        Santiago - Mexico City | Wed, Jan 14 | LATAM Airlines
        MEX 19:50
        8h 40m
        Direct
        SCL 07:30
        Mexico City - Santiago | Wed, Jan 21 | LATAM Airlines
        CAD 685 CAD 745
        8% OFF
        8% OFF
        CAD 745 CAD 685
      • SCL 07:25
        18h 30m
        1 stop
        MEX 22:55
        Santiago - Mexico City | Thu, Dec 25 | avianca
        NLU 10:06
        14h 29m
        1 stop
        SCL 03:35
        Mexico City - Santiago | Thu, Jan 1 | DM Airlines
        CAD 641 CAD 745
        14% OFF
        14% OFF
        CAD 745 CAD 641
      • SCL 01:35
        24h 20m
        1 stop
        MEX 22:55
        Santiago - Mexico City | Wed, Dec 31 | avianca
        MEX 00:40
        11h 40m
        1 stop
        SCL 15:20
        Mexico City - Santiago | Tue, Jan 6 | avianca
        CAD 642
        14% OFF
        CAD 745 CAD 642
      • SCL 06:00
        14h 26m
        1 stop
        NLU 17:26
        Santiago - Mexico City | Wed, Dec 24 | DM Airlines
        MEX 23:10
        13h 10m
        1 stop
        SCL 15:20
        Mexico City - Santiago | Wed, Dec 31 | avianca
        CAD 657
        12% OFF
        CAD 745 CAD 657
      • SCL 23:25
        8h 40m
        Direct
        MEX 05:05
        Santiago - Mexico City | Wed, Dec 24 | Aeromexico
        MEX 05:00
        16h 30m
        1 stop
        SCL 00:30
        Mexico City - Santiago | Wed, Dec 31 | avianca
        CAD 657
        12% OFF
        CAD 745 CAD 657
      • SCL 16:25
        22h 45m
        1 stop
        MEX 12:10
        Santiago - Mexico City | Tue, Dec 30 | avianca
        MEX 23:10
        13h 10m
        1 stop
        SCL 15:20
        Mexico City - Santiago | Wed, Jan 7 | avianca
        CAD 659
        12% OFF
        CAD 745 CAD 659
      • SCL 07:25
        22h 35m
        1 stop
        MEX 03:00
        Santiago - Mexico City | Thu, Dec 18 | avianca
        MEX 00:40
        11h 40m
        1 stop
        SCL 15:20
        Mexico City - Santiago | Thu, Dec 25 | avianca
        CAD 660
        11% OFF
        CAD 745 CAD 660
      • SCL 16:25
        13h 35m
        1 stop
        MEX 03:00
        Santiago - Mexico City | Sun, Dec 28 | avianca
        MEX 05:00
        16h 30m
        1 stop
        SCL 00:30
        Mexico City - Santiago | Sat, Jan 3 | avianca
        CAD 662
        11% OFF
        CAD 745 CAD 662
      • SCL 05:44
        19h 21m
        1 stop
        MEX 22:05
        Santiago - Mexico City | Fri, Dec 19 | Copa Airlines
        MEX 13:10
        28h 11m
        1 stop
        SCL 20:21
        Mexico City - Santiago | Wed, Dec 24 | Copa Airlines
        CAD 663
        11% OFF
        CAD 745 CAD 663
      • SCL 09:10
        8h 40m
        Direct
        MEX 14:50
        Santiago - Mexico City | Wed, Jan 21 | LATAM Airlines
        MEX 16:00
        11h 25m
        1 stop
        SCL 06:25
        Mexico City - Santiago | Wed, Jan 28 | LATAM Airlines
        CAD 675
        9% OFF
        CAD 745 CAD 675
      • SCL 06:00
        14h 26m
        1 stop
        NLU 17:26
        Santiago - Mexico City | Wed, Jan 14 | DM Airlines
        NLU 10:06
        14h 29m
        1 stop
        SCL 03:35
        Mexico City - Santiago | Thu, Jan 22 | DM Airlines
        CAD 680
        9% OFF
        CAD 745 CAD 680
      • SCL 13:00
        17h 25m
        1 stop
        MEX Invalid Date
        Santiago - Mexico City | Fri, Dec 19 | Normal Airline
        MEX 15:00
        6h
        Direct
        SCL 16:00
        Mexico City - Santiago | Sun, Dec 21 | Normal Airline
        Find More Flights
        Find More Flights
      • Cheapest nonstop
        SCL 23:25
        8h 40m
        Direct
        MEX 05:05
        Santiago - Mexico City | Wed, Dec 24 | Aeromexico
        CAD 352 CAD 388
        9% OFF
        9% OFF
        CAD 388 CAD 352
      • SCL 21:05
        17h 5m
        1 stop
        MEX 11:10
        Santiago - Mexico City | Tue, Feb 10 | Sky Airline
        CAD 324 CAD 388
        16% OFF
        16% OFF
        CAD 388 CAD 324
      • SCL 11:24
        26h 46m
        1 stop
        MEX 11:10
        Santiago - Mexico City | Wed, Feb 4 | JetSMART Airlines
        CAD 327 CAD 388
        16% OFF
        16% OFF
        CAD 388 CAD 327
      • SCL 23:05
        15h 5m
        1 stop
        MEX 11:10
        Santiago - Mexico City | Wed, Feb 4 | Sky Airline
        CAD 329
        15% OFF
        CAD 388 CAD 329
      • SCL 21:29
        16h 41m
        1 stop
        MEX 11:10
        Santiago - Mexico City | Tue, Feb 10 | JetSMART Airlines
        CAD 335
        14% OFF
        CAD 388 CAD 335
      • SCL 22:15
        15h 55m
        1 stop
        MEX 11:10
        Santiago - Mexico City | Tue, Feb 10 | LATAM Airlines
        CAD 346
        11% OFF
        CAD 388 CAD 346
      • SCL 05:59
        32h 11m
        1 stop
        MEX 11:10
        Santiago - Mexico City | Thu, Jan 15 | JetSMART Airlines
        CAD 347
        10% OFF
        CAD 388 CAD 347
      • SCL 06:00
        14h 26m
        1 stop
        NLU 17:26
        Santiago - Mexico City | Wed, Dec 24 | DM Airlines
        CAD 348
        10% OFF
        CAD 388 CAD 348
      • SCL 21:14
        16h 56m
        1 stop
        MEX 11:10
        Santiago - Mexico City | Sun, Feb 8 | JetSMART Airlines
        CAD 354
        9% OFF
        CAD 388 CAD 354
      • SCL 21:05
        17h 5m
        1 stop
        MEX 11:10
        Santiago - Mexico City | Tue, Jan 27 | Sky Airline
        CAD 357
        8% OFF
        CAD 388 CAD 357
      • SCL 13:00
        17h 25m
        1 stop
        MEX Invalid Date
        Santiago - Mexico City | Fri, Dec 19 | Normal Airline
        Find More Flights
        Find More Flights

Displayed flight fares from Santiago to Mexico City are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Flight Information for Santiago to Mexico City Flights

The distance between Santiago and Mexico City is 6,596.83km. It takes around 8 hours 38 minutes on average to fly from Santiago to Mexico City. Based on Trip.com's data, travel demand peaks in July. The off-season for travel is December.

Cheapest one-way flight priceCAD 324
Cheapest return ticket priceCAD 641
Off-season travel monthDecember
Peak season for travelJuly
Flight distance6,596.83km
Average flight time8 hours 38 minutes
Popular airlineAeromexico
Flight statistics for the Santiago–Mexico City route are based on aggregated booking data from Trip.com over the past 12 months.

When is the cheapest time to fly from Santiago to Mexico City?

The cheapest time for Santiago to Mexico City flights: Feb 15 to Feb 22 — one way flight prices from CAD 317.

Cheapest flights
From price
Search
  • 1421
  • 2128

  • Jan

    284
  • 411
  • 1118
  • 1825

  • Feb

    251
  • 18
  • 815
  • 1522

  • Mar

    221
  • 18
Displayed fare trends are based on Trip.com's aggregated average of the lowest flight prices from Santiago to Mexico City, calculated over the upcoming 10 weeks.

Flight FAQs

  • Which airlines offer the cheapest flights from Santiago (SCL) to Mexico City (MEX)?

    Based on Trip.com data, Sky Airline offers one-way fares as low as CAD 324 on Cheapest nonstop routes (e.g. SCL to MEX on Tue, Feb 10), while avianca offers Cheapest nonstop round-trips from CAD 641 departing on Thu, Dec 25 and returning on Thu, Jan 1.
  • At the moment, you can catch a direct flight from Santiago to Mexico City with the following airlines, including: Aeromexico Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.
  • It takes about 8 hours 38 minutes to fly from Santiago (SCL) to Mexico City (MEX).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santiago to Mexico City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • Based on Trip.com data in the past 4 weeks, there is 13 flight per week flying from Santiago to Mexico City. You can check the weekly schedule for popular airlines on this route below: Aeromexico: S/M/T/W/T/F/S -- AM011 (00:11)
  • To find best deals on flights from Santiago to Mexico City, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Tue, Feb 10, with one-way flights priced at just CAD 324.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Aeromexico.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Mexico City travel is around July.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Santiago to Mexico City is December, when demand for travel is lower.
  • After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Santiago to Mexico City on December 25, 2025 with avianca, with prices starting at CAD 640.
  • You can land at any one of the following hubs in Mexico City, with Arturo Merino Benitez International Airport to Mexico City International Airport (SCL-MEX) is by far the most common option on this route: Mexico City International Airport (MEX) Felipe angeles International Airport (NLU) Toluca International Airport (TLC).
  • The time difference between Mexico City and Santiago is 2h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.