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Buffalo to Mcghee Tyson Airport flight

Explore the cheapest one-way and round-trip flights from Buffalo to Mcghee Tyson Airport over the next 90 days, with one-way fares from US$150 and round-trip from US$227. Based on Trip.com's latest 7-day flight data.

    • Cheapest
      BUF 15:53
      3h 56m
      1 stop
      TYS 19:49
      Buffalo - Knoxville | Sat, Oct 31 | Delta Air Lines
      US$150 US$467
      68% off
      68% off
      US$467 US$150
    • BUF 19:52
      4h 7m
      1 stop
      TYS 23:59
      Buffalo - Knoxville | Mon, Nov 23 | United Airlines
      US$170 US$467
      64% off
      64% off
      US$467 US$170
    • BUF 14:55
      4h 41m
      1 stop
      TYS 19:36
      Buffalo - Knoxville | Sat, Nov 14 | United Airlines
      US$184 US$467
      61% off
      61% off
      US$467 US$184
    • BUF 05:50
      6h 38m
      1 stop
      TYS 12:28
      Buffalo - Knoxville | Sat, Oct 31 | American Airlines
      US$185
      60% off
      US$467 US$185
    • BUF 05:13
      5h 45m
      1 stop
      TYS 10:58
      Buffalo - Knoxville | Tue, Nov 3 | American Airlines
      US$185
      60% off
      US$467 US$185
    • BUF 06:00
      5h 30m
      1 stop
      TYS 11:30
      Buffalo - Knoxville | Tue, Nov 3 | United Airlines
      US$192
      59% off
      US$467 US$192
    • BUF 06:10
      4h 10m
      1 stop
      TYS 10:20
      Buffalo - Knoxville | Tue, Nov 24 | Delta Air Lines
      US$202
      56% off
      US$467 US$202
    • BUF 10:51
      5h 1m
      1 stop
      TYS 15:52
      Buffalo - Knoxville | Sat, Oct 31 | United Airlines
      US$202
      56% off
      US$467 US$202
    • BUF 06:00
      5h 30m
      1 stop
      TYS 11:30
      Buffalo - Knoxville | Thu, Oct 29 | United Airlines
      US$351
      25% off
      US$467 US$351
    • BUF 13:00
      17h 25m
      1 stop
      TYS 14:00
      Buffalo - Knoxville | Thu, Oct 29 | Normal Airline
      Find more flights
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    • BUF 15:53
      5h 44m
      1 stop
      TYS 21:37
      Buffalo - Knoxville | Fri, Nov 6 | Delta Air Lines
      TYS 11:45
      3h 28m
      1 stop
      BUF 15:13
      Knoxville - Buffalo | Sun, Nov 8 | Delta Air Lines
      US$227 US$397
      43% off
      43% off
      US$397 US$227
    • BUF 06:15
      4h 5m
      1 stop
      TYS 10:20
      Buffalo - Knoxville | Sat, Nov 14 | Delta Air Lines
      TYS 06:05
      7h 21m
      1 stop
      BUF 13:26
      Knoxville - Buffalo | Sat, Nov 21 | Delta Air Lines
      US$244 US$397
      39% off
      39% off
      US$397 US$244
    • BUF 12:11
      6h 22m
      1 stop
      TYS 18:33
      Buffalo - Knoxville | Sun, Dec 13 | Delta Air Lines
      TYS 18:17
      5h 48m
      1 stop
      BUF 00:05
      Knoxville - Buffalo | Tue, Dec 15 | Delta Air Lines
      US$278 US$397
      30% off
      30% off
      US$397 US$278
    • BUF 11:38
      4h 40m
      1 stop
      TYS 16:18
      Buffalo - Knoxville | Tue, Nov 10 | American Airlines
      TYS 07:00
      4h 23m
      1 stop
      BUF 11:23
      Knoxville - Buffalo | Tue, Nov 17 | American Airlines
      US$289
      27% off
      US$397 US$289
    • BUF 06:00
      5h 2m
      1 stop
      TYS 11:02
      Buffalo - Knoxville | Fri, Nov 13 | Delta Air Lines
      TYS 17:15
      5h 45m
      1 stop
      BUF 23:00
      Knoxville - Buffalo | Mon, Nov 16 | Delta Air Lines
      US$294
      26% off
      US$397 US$294
    • BUF 18:41
      5h 16m
      1 stop
      TYS 23:57
      Buffalo - Knoxville | Sun, Dec 20 | Delta Air Lines
      TYS 05:40
      5h 25m
      1 stop
      BUF 11:05
      Knoxville - Buffalo | Mon, Dec 21 | Delta Air Lines
      US$294
      26% off
      US$397 US$294
    • BUF 15:53
      3h 56m
      1 stop
      TYS 19:49
      Buffalo - Knoxville | Tue, Nov 10 | Delta Air Lines
      TYS 13:40
      7h 8m
      1 stop
      BUF 20:48
      Knoxville - Buffalo | Tue, Nov 17 | Delta Air Lines
      US$295
      26% off
      US$397 US$295
    • BUF 19:53
      4h 2m
      1 stop
      TYS 23:55
      Buffalo - Knoxville | Tue, Nov 3 | American Airlines
      TYS 07:17
      4h 6m
      1 stop
      BUF 11:23
      Knoxville - Buffalo | Mon, Nov 9 | American Airlines
      US$303
      24% off
      US$397 US$303
    • BUF 17:20
      5h 2m
      1 stop
      TYS 22:22
      Buffalo - Knoxville | Tue, Nov 3 | Delta Air Lines
      TYS 18:23
      5h 36m
      1 stop
      BUF 23:59
      Knoxville - Buffalo | Mon, Nov 9 | Delta Air Lines
      US$303
      24% off
      US$397 US$303
    • BUF 13:00
      17h 25m
      1 stop
      TYS 14:00
      Buffalo - Knoxville | Thu, Oct 29 | Normal Airline
      TYS 15:00
      6h
      Direct
      BUF 16:00
      Knoxville - Buffalo | Sat, Oct 31 | Normal Airline
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    • BUF 15:53
      3h 56m
      1 stop
      TYS 19:49
      Buffalo - Knoxville | Sat, Oct 31 | Delta Air Lines
      US$150 US$467
      68% off
      68% off
      US$467 US$150
    • BUF 19:52
      4h 7m
      1 stop
      TYS 23:59
      Buffalo - Knoxville | Mon, Nov 23 | United Airlines
      US$170 US$467
      64% off
      64% off
      US$467 US$170
    • BUF 06:10
      4h 10m
      1 stop
      TYS 10:20
      Buffalo - Knoxville | Tue, Nov 24 | Delta Air Lines
      US$202 US$467
      56% off
      56% off
      US$467 US$202
    • BUF 14:55
      4h 41m
      1 stop
      TYS 19:36
      Buffalo - Knoxville | Sat, Nov 14 | United Airlines
      US$184
      61% off
      US$467 US$184
    • BUF 06:00
      4h 54m
      1 stop
      TYS 10:54
      Buffalo - Knoxville | Thu, Oct 29 | Delta Air Lines
      US$373
      20% off
      US$467 US$373
    • BUF 10:51
      5h 1m
      1 stop
      TYS 15:52
      Buffalo - Knoxville | Sat, Oct 31 | United Airlines
      US$202
      56% off
      US$467 US$202
    • BUF 06:00
      5h 30m
      1 stop
      TYS 11:30
      Buffalo - Knoxville | Tue, Nov 3 | United Airlines
      US$192
      59% off
      US$467 US$192
    • BUF 06:00
      5h 30m
      1 stop
      TYS 11:30
      Buffalo - Knoxville | Thu, Oct 29 | United Airlines
      US$351
      25% off
      US$467 US$351
    • BUF 05:13
      5h 45m
      1 stop
      TYS 10:58
      Buffalo - Knoxville | Tue, Nov 3 | American Airlines
      US$185
      60% off
      US$467 US$185
    • BUF 13:00
      17h 25m
      1 stop
      TYS 14:00
      Buffalo - Knoxville | Thu, Oct 29 | Normal Airline
      Find more flights
      Find more flights

Displayed flight fares from Buffalo to Knoxville are based on average prices across airlines for the next 3 months, according to the latest Trip.com database.

Which airlines are the most popular for Buffalo to Mcghee Tyson Airport flights?

Delta Air Lines logo Delta Air Lines

Flight Schedule from Buffalo to Mcghee Tyson Airport

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA1203

    Buffalo Niagara International Airport

    12:52

    BUF

    1h 57m

    Direct

    14:49

    CLT

    S M T W T F S
    Search

  2. AA6445

    Charlotte Douglas International Airport

    15:35

    CLT

    1h 13m

    Direct

    16:48

    TYS

    S M - - - - S

  3. DL3847

    Buffalo Niagara International Airport

    15:53

    BUF

    1h 16m

    Direct

    17:09

    DTW

    - - T W T F -
    Search

  4. DL5138

    Detroit Metropolitan Wayne County Airport

    19:46

    DTW

    1h 45m

    Direct

    21:31

    TYS

    S M T W T F S

  5. DL2898

    Buffalo Niagara International Airport

    06:25

    BUF

    1h 19m

    Direct

    07:44

    DTW

    S M T W T F S
    Search

  6. DL5347

    Detroit Metropolitan Wayne County Airport

    10:21

    DTW

    1h 50m

    Direct

    12:11

    TYS

    S M T W T F S

  7. UA4270

    Buffalo Niagara International Airport

    19:52

    BUF

    1h 26m

    Direct

    21:18

    IAD

    S - - W T - S
    Search

  8. UA4304

    Dulles International Airport

    22:10

    IAD

    1h 49m

    Direct

    23:59

    TYS

    S M T W T - S

  9. UA4255

    Buffalo Niagara International Airport

    10:35

    BUF

    1h 20m

    Direct

    11:55

    IAD

    - M T - - - S
    Search

  10. UA4070

    Dulles International Airport

    12:55

    IAD

    1h 49m

    Direct

    14:44

    TYS

    S M T W T F -

  11. AA3848

    Buffalo Niagara International Airport

    06:00

    BUF

    1h 28m

    Direct

    07:28

    DCA

    - - T W T F -
    Search

  12. AA5109

    Ronald Reagan Washington National Airport

    08:25

    DCA

    2h

    Direct

    10:25

    TYS

    - - T W T F -

  13. AA1203

    Buffalo Niagara International Airport

    12:52

    BUF

    1h 57m

    Direct

    14:49

    CLT

    S M T W T F S
    Search

  14. AA5159

    Charlotte Douglas International Airport

    15:07

    CLT

    1h 11m

    Direct

    16:18

    TYS

    - - T W T F -

  15. UA4291

    Buffalo Niagara International Airport

    15:00

    BUF

    1h 27m

    Direct

    16:27

    IAD

    S M T W T F -
    Search

  16. UA4914

    Dulles International Airport

    17:45

    IAD

    1h 50m

    Direct

    19:35

    TYS

    S M T W T F S

  17. DL2664

    Buffalo Niagara International Airport

    06:05

    BUF

    2h 30m

    Direct

    08:35

    ATL

    S M T W T F S
    Search

  18. DL1743

    Hartsfield–Jackson Atlanta International Airport

    10:10

    ATL

    1h 5m

    Direct

    11:15

    TYS

    S M T W T - S

  19. UA3715

    Buffalo Niagara International Airport

    10:45

    BUF

    1h 35m

    Direct

    12:20

    EWR

    S M T W T F S
    Search

  20. UA4186

    Newark Liberty International Airport

    13:40

    EWR

    2h 12m

    Direct

    15:52

    TYS

    S M T W T F S
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What to know about flights from Buffalo to Mcghee Tyson Airport?

Cheapest one-way flight price US$150
Off-season travel month October
Peak season for travel December

FAQs for Buffalo to Mcghee Tyson Airport Flights

  • When are flight tickets from Buffalo (BUF) to Knoxville (TYS) the cheapest?

    Airlines adjust prices for flights from Buffalo to Knoxville based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • According to Trip.com's data, the lowest price is around US$425.
  • There are 1 airport(s) in Knoxville (TYS): Mcghee Tyson Airport.
  • One-way flights from Buffalo to Mcghee Tyson Airport currently start from US$150, and round-trip fares start from US$227. The lowest fare is currently available on flights operated by Delta Air Lines departing on Sat, Oct 31. Fares are subject to change based on availability.
  • Enter your Buffalo and Mcghee Tyson Airport, select your departure date and number of passengers, then compare flights by price, flight duration and baggage allowance. Once you've chosen a fare, review the change and cancellation policy, fill in your passenger details and pay to receive your booking confirmation.
  • Yes. American Airlines operate direct flights from Buffalo to Mcghee Tyson Airport. The flight time is approximately 1 hour 15 minutes, with about 1 flights per week. Actual flight frequency may vary by season.
  • The latest flight from Buffalo to Mcghee Tyson Airport departs at 07:00, with approximately 1 flights per day. Flight schedules may change, so please check the latest departure times before travelling.
  • Knoxville has 1 airports reachable by flights departing from Buffalo, including Mcghee Tyson Airport. When choosing an airport, consider its distance to the city centre and route coverage.

Find Cheap Flights with Trip.com

Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed on this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, Wi-Fi, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within the last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.