Romantic Hotels in Santo Domingo

Welcome to Casas del XVI, Vignette Collection a boutique hotel in Santo Domingo, Dominican Republic, where every stay unfolds differently. Located in the heart of the Colonial City, a UNESCO World Heritage Site, our hotel connects you with the rich history and culture of the Dominican Republic. Just a few steps away you will find the House of Columbus, the Ozama Fortress Museum, the National Pantheon and the First Cathedral of the Americas. Here we do not offer traditional rooms, but a collection of restored historic houses—each with its own character and architecture. Enjoy plunge pools, tranquil courtyards and curated local activations. Every space blends heritage, art and contemporary luxury for an intimate and unforgettable experience in one of the most fascinating destinations in the world. Discover Santo Domingo from within, living as if at house, and touched with a personal and instinctive approach to hospitality. Casas del XVI, Vignette Collection redefines hospitality in the Dominican Republic.